Monday, 8 December 2014

Get The Winning Edge - Iron is a trace mineral that is highly significant to endurance athletes

Get The Winning Edge with Iron 

Russell Setright

Iron is a trace mineral that is highly significant to #endurance #athletes. Iron is critical to optimal athletic performance because of its role in energy metabolism, oxygen transport, and acid-base balance. low iron levels in athletes are common and one of the reasons for poor results during competitive events and exercise programs. Endurance athletes are at increased risk for suboptimal iron status, with potential negative consequences on performance (Hinton PS. Iron and the endurance athlete. Appl Physiol Nutr Metab. 2014 Sep;39(9):1012-8).

Studies have found that more than 50 per cent of competitive runners have iron deficiency at a level that can effect red blood cell production and athletic performance.

Women at higher risk: 
Recent studies have documented poor iron status and associated declines in both cognitive and physical performance in female athletes. In addition to low iron status low vitamin D and calcium status have been observed in female athletes, which can be associated with injuries, such as stress fracture, and limit a female athlete's ability to participate in regular physical activity. (McClung JP et al. Female athletes: A population at risk of vitamin and mineral deficiencies affecting health and performance J Trace Elem Med Biol. 2014 Jul 5).
  
A 2008 study by researchers at the University of Minnesota found that 89 percent of the members of a women’s college cross country team were anaemic at one time or another during the season

Iron Inflammation, athletes and Hepcidin
Hepcidin is the predominant negative regulator of iron absorption in the small intestine, iron transport across the placenta, and iron release from macrophages. And the synthesis of hepcidin is greatly stimulated by inflammation, trauma or by iron overload.

During the body’s inflammatory process, hepcidin is overproduced and as a negative regulator of iron this increases the risk of iron deficiency anaemia.
Inflammation and trauma, commonly caused by damage to joints and muscles during heavy exercise such as triathlons and marathons is one of the main causes of iron deficiency anaemia in athletes.

This inflammation causes an increase in hepcidin which in turn reduces iron adsorption and release from the body stores. If high levels of hepcidin are present, iron adsorption is reduced and as a result oral iron supplements are unlikely to be effective.

There are two factors that need to be addressed if adequate iron levels are to be maintained in the serious athlete.
1.      Ensure that the dietary intake of iron is adequate. If relying on cereal or non-haem iron as a major dietary source it is important to include vitamin C rich foods at the same meal or a vitamin C supplement as without adequate vitamin C non-haem iron is only about 30 per cent bioavailable.
2.      Reduce inflammation to increase bio availability and adsorption of iron by;
(a)    Wearing shock absorbing footwear
(b)    Use support strapping on joints that have had injury.
(c)     Supplement with curcumin (turmeric) may reduce inflammation mediated hepcidin production
(d)    Fish oil and Lyprinol for their natural anti-inflammatory activity.
 
1.     Sihler KC, et al Hepcidin in trauma: linking injury, inflammation, and anemia. J Trauma. 2010 Oct;69(4):831-7
2.     Peeling P, et al. Iron status and the acute post-exercise hepcidin response in athletes. PLoS One. 2014 Mar 25;9(3):e93002.
3.     Sim M et al. Iron regulation in athletes: exploring the menstrual cycle and effects of different exercise modalities on hepcidin production. Int J Sport Nutr Exerc Metab. 2014 Apr;24(2):177-87.

4.     Fatih N, et al. Natural and synthetic STAT3 inhibitors reduce hepcidin expression in differentiated mouse hepatocytes expressing the active phosphorylated STAT3 form. J Mol Med (Berl). 2010 May;88(5):477-86

Bio Iron supplement may assist if your dietary intake is low
Contains;
Ferrous fumarate (iron 5 mg)15.3 mg
Vitamin C (Ascorbic acid)100 mg
Folic acid166.5 µg
Vitamin B12 (Cyanocobalamin)50 µg
Urtica dioica (Nettle) herb powder100 mg

Saturday, 6 December 2014

Life Survival Medics for Movies, Sports and all events - we will look after you












The amino acid L-carnitine has been found to significantly improve cardiac health

Latest Health News

Russell Setright

L-Carnitine improves survival after a heart attack

The amino acid L-carnitine found in meat and widely available as an over-the-counter nutritional supplement has been found to significantly improve cardiac health in patients after a heart attack, The findings, based on analysis of key controlled trials, associate L-carnitine with significant reduction in death from all causes and a highly significant reduction in ventricular arrhythmias and angina attacks following a heart attack, compared with placebo or control.



James J. DiNicolantonio, Carl J. Lavie, Hassan Fares, Arthur R. Menezes and James H. O’Keefe. L-Carnitine in the Secondary Prevention of Cardiovascular Disease: Systematic Review and Meta-analysis. Mayo Clinic Proceedings, June 2013; Volume 88, Issue 6 

Friday, 5 December 2014

Genius says vitamin pills may make him smarter

Can Popping Supplements Make You Smarter?

One of the smartest men Rick Rosner who has an IQ of 192 told Business Insider Australia Dec 3, 2014 that he takes the following  pill concoction to boosts his brain function enough to make him even smarter, and delay brain ageing. 

Genius's pill list:

  • Omega-3 fish oil capsules
  • Half an aspirin
  • Metformin
  • Metoprolol
  • Glisodin
  • Avodart
  • Astragalus
  • Fiber gummies  
  • Fat blockers
  • Prescription and non-prescription drugs to lower cholesterol
  • Curcumin 
  • ToCoQ10
  • L-carnosine
  • ALA and acetyl L-carnitine
  • Vitamin D3
  • Vitamin C
  • Vitamin E with selenium and also Gamma E
  • Lycopene
  • TMG (trimethylglycene)
  • Calcium
  • Benfotamine
  • N-acetyl cysteine
  • Mangosteen/pomegranate/noni complex
  • Vitamin K
  • Horse chestnut
  • Quercetin & bromelain
  • Coffee
  • Phosphatidylserine
  • DMAE
  • Aminoguanidine
  • Centrophenoxine
  • Piracetam
  • Cognitex from Life Extension
  • Vinpocetine (occasionally)
  • Methylene blue

Wow, The list looks good and there is some good evidence to support it however I'm happy I'm not paying for them. Have a read at http://www.businessinsider.com.au/rick-rosner-iq-and-health-2014-12

Along with increasing exercise, maintenance of ideal weight and a diet low in salt and alcohol, increases omega-3 dietary intake from oily fish or supplements could be a positive step.

Fish Oil can help fight cardiovascular disease and stroke.

Russell Setright

Omerga-3 fatty acids supplements again found of benefit in the fight against high blood pressure (hypertension).
Hypertension is a major risk factor in the development of cardiovascular disease and stroke and any positive effects that improving lifestyle and diet has on blood pressure reduction reduces the incidence of this life threatening disease.

A new meta-analysis of 70 studies published in the American Journal of Hypertension March 1014, has found that supplementing with  more than 2,000mg of omega 3  fatty acids (EPA+DHA ) found in fish oil, had a positive effect in reducing both systolic ( the upper measurement) and Diastolic ( the lower measurement) blood pressure.

The strongest effects of the omega-3 supplements were observed among untreated hypertensive subjects and these reductions were found to be greater than reducing dietary salt or alcohol.

These results again show the importance of dietary omega-3 oils for cardiovascular health. Along with increasing exercise, maintenance of ideal weight and a diet low in salt and alcohol, increases omega-3 dietary intake from oily fish or supplements could be a positive step.

  1. Long-Chain Omega-3 Fatty Acids Eicosapentaenoic Acid and Docosahexaenoic Acid and Blood Pressure: A Meta-Analysis of Randomized Controlled Trial Am J Hypertens (2014) doi: 10.1093/ajh/hpu024 First published online: March 6, 2014 

Thursday, 4 December 2014

ACUTE BRONCHITIS

ACUTE BRONCHITIS

Russell Setright

Bronchitis is very often acute in children whereas as it is usually a chronic condition in adolescents and adults. Bronchitis is inflammation of the bronchi or large air passages that lead to the lungs. Living in damp environments, eat poorly, are exposed to cold, are overtired, or who have caught a cold or flu virus may develop bronchitis. Acute bronchitis can be caused by other viruses, allergies, bacteria or environmental irritants.
The symptoms include coughing at night, which is initially unproductive at first but may develop and produce thick yellow phlegm, noisy rattling coughing, and a fever.

Is acute Bronchitis contagious?
As acute bronchitis describes a group of symptoms (including airway inflammation, over-production of phlegm, and cough it can be contagious if the cause is viral or bacterial. However, if the cause of the bronchitis is due to smoking, air pollution, or other inhaled irritants, it is not contagious.

What can I do to help relieve the symptoms?
At night, when the coughing is at its worst, a vaporiser may help(either a commercial one or a bowl of boiling water which can hold its heat). You can make your own vaporiser liquid or there are many brands to choose from pharmacy and health food outlets.

Typical Vaporiser liquid: each 5ml contains:
Camphor                                                             250mg
Eucalyptus oil                                                       0.5ml
Wintergreen oil                                     0.1ml
Menthol                                                                500mg
Tea tree oil                                                          0.2ml
In a base of propylene glycol to 100 per cent

The above liquid is to be used in steam vaporiser units for the treatment of the coughs of colds and bronchitis. This will ease breathing and loosen the phlegm. Also to help loosen phlegm and soothe the inflamed air passages, use the herbs liquorice, horehound, mullein, pleurisy root echinacea In combination, these will help relieve the coughing and make it more productive.
Cod liver oil has been used for decades for colds flu and bronchitis. The essential fatty acids in the oil have an anti-inflammatory effect and the vitamin A helps strengthen the mucous membranes. Garlic, vitamin C, and echinacea may help prevent further infection.

Clinically proven treatment
For centuries, the herb Pelargonium sidoides has been traditionally used in South Africa for the treatment of respiratory diseases. The common name for this herb is umckaloabo which is derived from the Zulu language and means “heavy cough”. Today specialised farms using ecological cultivation methods produce P. sidoides.

This herb is now available in Australia from Blackmores in their product  Kaloba® which has been clinically proven to provide relief of acute bronchitis symptoms after 7 days (45% of the patients taking Kaloba® experienced recovery after 7 days compared to 6.4% taking a placebo), it also can help speed up recovery. 

Wednesday, 3 December 2014

Vitamin D supplements can reduce COPD lung disease flare-ups by over 40%

Vitamin D reduces lung disease flare-ups by over 40 percent



Vitamin D supplements can reduce COPD lung disease flare-ups by over 40% in patients with a vitamin D deficiency - according to new research from Queen Mary University of London. COPD (chronic obstructive pulmonary disease) includes conditions such as chronic bronchitis and emphysema, and is thought to affect more than 3 million people in the UK.

The NIHR-funded randomised trial, published in the journal Lancet Respiratory Medicine, included 240 patients with COPD in and around London. Half of the patients (122) received vitamin D supplements (6 x 2-monthly oral doses of 3mg) and the other half (118) received an equivalent placebo. The risk, severity and duration of flare-ups was then compared between the two groups.
Flare-ups (also referred to as 'exacerbations') are when a COPD patient's usual symptoms (coughing, excess mucus, shortness of breath, tightness in chest) get worse and stay worse, sometimes resulting in hospitalisation.

Patients with a vitamin D deficiency benefited dramatically from taking the supplements but the striking reduction in flare-ups was not seen among patients who had a higher vitamin D status at the start of the trial. However, researchers did find vitamin D supplementation modestly reduced the severity and duration of flare-up symptoms in all patients in the vitamin D group, regardless of their baseline vitamin D levels, compared to the placebo group.

This is the first clinical trial to investigate the impact of vitamin D supplementation on severity and duration of COPD symptoms. One previous trial has linked vitamin D to a reduction in COPD disease flare ups but this was limited to patients with very severe conditions. This trial is larger and studied patients with a much broader spectrum of diseases, ranging from mild to severe.

Professor Adrian Martineau, Lead Author, Queen Mary University of London, comments: "Flare-ups of chronic bronchitis and emphysema (COPD) can be debilitating for patients, sometimes leading to hospitalisation and even death. Our research has shown how an inexpensive vitamin supplement can significantly reduce the risk of flare-ups for patients who are vitamin D deficient, which could have a major public health benefit. Our findings suggest that patients with COPD should have their vitamin D status tested and should begin taking supplements if their levels are found to be low."


PUBLIC RELEASE DATE:
1-Dec-2014 
  1. Adrian R Martineau, Wai Yee James, Richard L Hooper, Neil C Barnes, David A Jolliffe, Claire L Greiller, Kamrul Islam, David McLaughlin, Angshu Bhowmik, Peter M Timms, Raj K Rajakulasingam, Marion Rowe, Timothy R Venton, Aklak B Choudhury, David E Simcock, Mark Wilks, Amarjeet Degun, Zia Sadique, William R Monteiro, Christopher J Corrigan, Catherine M Hawrylowicz, Christopher J Griffiths. Vitamin D3 supplementation in patients with chronic obstructive pulmonary disease (ViDiCO): a multicentre, double-blind, randomised controlled trial. The Lancet Respiratory Medicine, 2014; DOI: 10.1016/S2213-2600(14)70255-3